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A hominoid-specific endogenous retrovirus may have rewired the gene regulatory network shared between primordial germ cells and naïve pluripotent cells

Mammalian germ cells stem from primordial germ cells (PGCs). Although the gene regulatory network controlling the development of germ cells such as PGCs is critical for ensuring gamete integrity, substantial differences exist in this network among mammalian species, suggesting that this network has...

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Detalles Bibliográficos
Autores principales: Ito, Jumpei, Seita, Yasunari, Kojima, Shohei, Parrish, Nicholas F., Sasaki, Kotaro, Sato, Kei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9128956/
https://www.ncbi.nlm.nih.gov/pubmed/35551519
http://dx.doi.org/10.1371/journal.pgen.1009846