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Subnuclear localisation is associated with gene expression more than parental origin at the imprinted Dlk1-Dio3 locus

At interphase, de-condensed chromosomes have a non-random three-dimensional architecture within the nucleus, however, little is known about the extent to which nuclear organisation might influence expression or vice versa. Here, using imprinting as a model, we use 3D RNA- and DNA-fluorescence-in-sit...

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Detalles Bibliográficos
Autores principales: Mashoodh, Rahia, Hülsmann, Lisa C., Dearden, Frances L., Takahashi, Nozomi, Edwards, Carol, Ferguson-Smith, Anne C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9129038/
https://www.ncbi.nlm.nih.gov/pubmed/35482825
http://dx.doi.org/10.1371/journal.pgen.1010186