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Subnuclear localisation is associated with gene expression more than parental origin at the imprinted Dlk1-Dio3 locus
At interphase, de-condensed chromosomes have a non-random three-dimensional architecture within the nucleus, however, little is known about the extent to which nuclear organisation might influence expression or vice versa. Here, using imprinting as a model, we use 3D RNA- and DNA-fluorescence-in-sit...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9129038/ https://www.ncbi.nlm.nih.gov/pubmed/35482825 http://dx.doi.org/10.1371/journal.pgen.1010186 |