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Biclustering reveals potential knee OA phenotypes in exploratory analyses: Data from the Osteoarthritis Initiative

OBJECTIVE: To apply biclustering, a methodology originally developed for analysis of gene expression data, to simultaneously cluster observations and clinical features to explore candidate phenotypes of knee osteoarthritis (KOA) for the first time. METHODS: Data from the baseline Osteoarthritis Init...

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Detalles Bibliográficos
Autores principales: Nelson, Amanda E., Keefe, Thomas H., Schwartz, Todd A., Callahan, Leigh F., Loeser, Richard F., Golightly, Yvonne M., Arbeeva, Liubov, Marron, J. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9129051/
https://www.ncbi.nlm.nih.gov/pubmed/35609053
http://dx.doi.org/10.1371/journal.pone.0266964