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Artificial microRNA guide strand selection from duplexes with no mismatches shows a purine‐rich preference for virus‐ and non‐virus‐based expression vectors in plants

Artificial microRNA (amiRNA) technology has allowed researchers to direct efficient silencing of specific transcripts using as few as 21 nucleotides (nt). However, not all the artificially designed amiRNA constructs result in selection of the intended ~21‐nt guide strand amiRNA. Selection of the miR...

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Detalles Bibliográficos
Autores principales: Kuo, Yen‐Wen, Falk, Bryce W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9129084/
https://www.ncbi.nlm.nih.gov/pubmed/35113475
http://dx.doi.org/10.1111/pbi.13786