Genetic and Structural Analysis of SARS-CoV-2 Spike Protein for Universal Epitope Selection

Evaluation of immunogenic epitopes for universal vaccine development in the face of ongoing SARS-CoV-2 evolution remains a challenge. Herein, we investigate the genetic and structural conservation of an immunogenically relevant epitope (C662–C671) of spike (S) protein across SARS-CoV-2 variants to d...

Descripción completa

Detalles Bibliográficos
Autores principales: Markosian, Christopher, Staquicini, Daniela I., Dogra, Prashant, Dodero-Rojas, Esteban, Lubin, Joseph H., Tang, Fenny H.F., Smith, Tracey L., Contessoto, Vinícius G., Libutti, Steven K., Wang, Zhihui, Cristini, Vittorio, Khare, Sagar D., Whitford, Paul C., Burley, Stephen K., Onuchic, José N., Pasqualini, Renata, Arap, Wadih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Methods
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9129195/
https://www.ncbi.nlm.nih.gov/pubmed/35511693
http://dx.doi.org/10.1093/molbev/msac091

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9129195/
https://www.ncbi.nlm.nih.gov/pubmed/35511693
http://dx.doi.org/10.1093/molbev/msac091

Ejemplares similares