Cargando…
Genetic and Structural Analysis of SARS-CoV-2 Spike Protein for Universal Epitope Selection
Evaluation of immunogenic epitopes for universal vaccine development in the face of ongoing SARS-CoV-2 evolution remains a challenge. Herein, we investigate the genetic and structural conservation of an immunogenically relevant epitope (C662–C671) of spike (S) protein across SARS-CoV-2 variants to d...
Autores principales: | Markosian, Christopher, Staquicini, Daniela I., Dogra, Prashant, Dodero-Rojas, Esteban, Lubin, Joseph H., Tang, Fenny H.F., Smith, Tracey L., Contessoto, Vinícius G., Libutti, Steven K., Wang, Zhihui, Cristini, Vittorio, Khare, Sagar D., Whitford, Paul C., Burley, Stephen K., Onuchic, José N., Pasqualini, Renata, Arap, Wadih |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9129195/ https://www.ncbi.nlm.nih.gov/pubmed/35511693 http://dx.doi.org/10.1093/molbev/msac091 |
Ejemplares similares
-
Apropos of Universal Epitope Discovery for COVID-19 Vaccines: A Framework for Targeted Phage Display-Based Delivery and Integration of New Evaluation Tools
por: Markosian, Christopher, et al.
Publicado: (2021) -
Design and proof-of-concept for targeted phage-based COVID-19 vaccination strategies with a streamlined cold-free supply chain
por: Staquicini, Daniela I., et al.
Publicado: (2021) -
Design and proof of concept for targeted phage-based COVID-19 vaccination strategies with a streamlined cold-free supply chain
por: Staquicini, Daniela I., et al.
Publicado: (2021) -
Structural models of SARS-CoV-2 Omicron variant in complex with ACE2 receptor or antibodies suggest altered binding interfaces
por: Lubin, Joseph H., et al.
Publicado: (2021) -
A modeling-based approach to optimize COVID-19 vaccine dosing schedules for improved protection
por: Dogra, Prashant, et al.
Publicado: (2023)