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Notch controls the cell cycle to define leader versus follower identities during collective cell migration

Coordination of cell proliferation and migration is fundamental for life, and its dysregulation has catastrophic consequences, such as cancer. How cell cycle progression affects migration, and vice versa, remains largely unknown. We address these questions by combining in silico modelling and in viv...

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Detalles Bibliográficos
Autores principales: Alhashem, Zain, Feldner-Busztin, Dylan, Revell, Christopher, Alvarez-Garcillan Portillo, Macarena, Camargo-Sosa, Karen, Richardson, Joanna, Rocha, Manuel, Gauert, Anton, Corbeaux, Tatianna, Milanetto, Martina, Argenton, Francesco, Tiso, Natascia, Kelsh, Robert N, Prince, Victoria E, Bentley, Katie, Linker, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9129880/
https://www.ncbi.nlm.nih.gov/pubmed/35438077
http://dx.doi.org/10.7554/eLife.73550