Transcriptome-wide mapping reveals a diverse dihydrouridine landscape including mRNA

Dihydrouridine is a modified nucleotide universally present in tRNAs, but the complete dihydrouridine landscape is unknown in any organism. We introduce dihydrouridine sequencing (D-seq) for transcriptome-wide mapping of D with single-nucleotide resolution and use it to uncover novel classes of dihy...

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Detalles Bibliográficos
Autores principales: Draycott, Austin S., Schaening-Burgos, Cassandra, Rojas-Duran, Maria F., Wilson, Loren, Schärfen, Leonard, Neugebauer, Karla M., Nachtergaele, Sigrid, Gilbert, Wendy V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Discovery Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9129914/
https://www.ncbi.nlm.nih.gov/pubmed/35609439
http://dx.doi.org/10.1371/journal.pbio.3001622

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9129914/
https://www.ncbi.nlm.nih.gov/pubmed/35609439
http://dx.doi.org/10.1371/journal.pbio.3001622

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