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Reconstitution and mechanistic dissection of the human microtubule branching machinery

Branching microtubule (MT) nucleation is mediated by the augmin complex and γ-tubulin ring complex (γ-TuRC). However, how these two complexes work together to promote this process remains elusive. Here, using purified components from native and recombinant sources, we demonstrate that human augmin a...

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Detalles Bibliográficos
Autores principales: Zhang, Yaqian, Hong, Xing, Hua, Shasha, Jiang, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9129923/
https://www.ncbi.nlm.nih.gov/pubmed/35604367
http://dx.doi.org/10.1083/jcb.202109053