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Zizhu Ointment Accelerates Wound-Healing of Diabetic Ulcers through Promoting M2 Macrophage Polarization via Downregulating the Notch4 Signaling Pathway

OBJECTIVE: The long-term clinical practice shows that Zizhu ointment (ZZO) is an empirical formula for the treatment of diabetic ulcers (DUs). In this study, we investigated the underlying mechanism of ZZO in the treatment of DU mice. METHODS: Through streptozotocin induction and high-fat diet, a DU...

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Detalles Bibliográficos
Autores principales: Huang, Renyan, Hu, Xiaoming, Li, Wenhui, Wang, Lixiang, Fan, Weijing, Han, Qiang, Guo, Fang, Liu, Guobin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9129934/
https://www.ncbi.nlm.nih.gov/pubmed/35619768
http://dx.doi.org/10.1155/2022/5173836