Inhibiting Microglia-Derived NLRP3 Alleviates Subependymal Edema and Cognitive Dysfunction in Posthemorrhagic Hydrocephalus after Intracerebral Hemorrhage via AMPK/Beclin-1 Pathway

For posthemorrhagic hydrocephalus (PHH) patients, whether occur subependymal edema indicates poor outcomes, partially manifested as cognitive impairment. In the brain, NLRP3 inflammasome mainly derived from microglia/macrophages is involved in proinflammatory and neurodeficits after hemorrhage, and...

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Detalles Bibliográficos
Autores principales: Zhang, Zhaoqi, Guo, Peiwen, Huang, Suna, Jia, Zhengcai, Chen, Tunan, Liu, Xin, Feng, Hua, Chen, Yujie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9129981/
https://www.ncbi.nlm.nih.gov/pubmed/35620574
http://dx.doi.org/10.1155/2022/4177317

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9129981/
https://www.ncbi.nlm.nih.gov/pubmed/35620574
http://dx.doi.org/10.1155/2022/4177317

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