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Endotrophin, a collagen type VI-derived matrikine, reflects the degree of renal fibrosis in patients with IgA nephropathy and in patients with ANCA-associated vasculitis

BACKGROUND: Renal fibrosis is the hallmark of chronic kidney disease (CKD) and is characterized by an imbalanced extracellular matrix remodelling. Endotrophin (ETP) is a signalling molecule released from collagen type VI (COL VI). ETP can be measured by the PRO-C6 assay, which quantifies the levels...

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Detalles Bibliográficos
Autores principales: Sparding, Nadja, Genovese, Federica, Rasmussen, Daniel Guldager Kring, Karsdal, Morten Asser, Neprasova, Michaela, Maixnerova, Dita, Satrapova, Veronika, Frausova, Doubravka, Hornum, Mads, Bartonova, Lenka, Honsova, Eva, Kollar, Marek, Koprivova, Helena, Hruskova, Zdenka, Tesar, Vladimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9130028/
https://www.ncbi.nlm.nih.gov/pubmed/33914059
http://dx.doi.org/10.1093/ndt/gfab163