STIM1 Deficiency In Intestinal Epithelium Attenuates Colonic Inflammation and Tumorigenesis by Reducing ER Stress of Goblet Cells

BACKGROUND & AIMS: As an indispensable component of store-operated Ca(2+) entry, stromal interaction molecule 1 (STIM1) is known to promote colorectal cancer and T-cell–mediated inflammatory diseases. However, whether the intestinal mucosal STIM1 is involved in inflammatory bowel diseases (IBDs)...

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Detalles Bibliográficos
Autores principales: Liang, Xiaojing, Xie, Jiansheng, Liu, Hao, Zhao, Rongjie, Zhang, Wei, Wang, Haidong, Pan, Hongming, Zhou, Yubin, Han, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9130113/
https://www.ncbi.nlm.nih.gov/pubmed/35367664
http://dx.doi.org/10.1016/j.jcmgh.2022.03.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9130113/
https://www.ncbi.nlm.nih.gov/pubmed/35367664
http://dx.doi.org/10.1016/j.jcmgh.2022.03.007

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