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STIM1 Deficiency In Intestinal Epithelium Attenuates Colonic Inflammation and Tumorigenesis by Reducing ER Stress of Goblet Cells

BACKGROUND & AIMS: As an indispensable component of store-operated Ca(2+) entry, stromal interaction molecule 1 (STIM1) is known to promote colorectal cancer and T-cell–mediated inflammatory diseases. However, whether the intestinal mucosal STIM1 is involved in inflammatory bowel diseases (IBDs)...

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Detalles Bibliográficos
Autores principales:	Liang, Xiaojing, Xie, Jiansheng, Liu, Hao, Zhao, Rongjie, Zhang, Wei, Wang, Haidong, Pan, Hongming, Zhou, Yubin, Han, Weidong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9130113/ https://www.ncbi.nlm.nih.gov/pubmed/35367664 http://dx.doi.org/10.1016/j.jcmgh.2022.03.007

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