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Differential effects of acute and chronic antagonist and an irreversible antagonist treatment on cocaine self-administration behavior in rats

According to pharmacological theory, the magnitude of an agonist-induced response is related to the number of receptors occupied. If there is a receptor reserve, when the number of receptors is altered the fractional occupancy required to maintain this set number of receptors will change. Therefore,...

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Detalles Bibliográficos
Autores principales:	Wetzel, Hanna N., Tsibulsky, Vladimir L., Norman, Andrew B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9130121/ https://www.ncbi.nlm.nih.gov/pubmed/35610298 http://dx.doi.org/10.1038/s41598-022-12798-x

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