DNA and RNA oxidative damage in the retina is associated with ganglion cell mitochondria

This study examines retinas from a rat glaucoma model for oxidized nucleosides 8OHdG and 8OHG, biomarkers for oxidative damage of DNA and RNA, respectively. Immunohistochemical data indicate a predominant localization of 8OHdG/8OHG in retinal ganglion cells (RGCs). The levels for these oxidized DNA/...

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Detalles Bibliográficos
Autores principales: Gu, Lei, Kwong, Jacky M., Caprioli, Joseph, Piri, Natik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9130135/
https://www.ncbi.nlm.nih.gov/pubmed/35610341
http://dx.doi.org/10.1038/s41598-022-12770-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9130135/
https://www.ncbi.nlm.nih.gov/pubmed/35610341
http://dx.doi.org/10.1038/s41598-022-12770-9

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