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Disruption of β-catenin-mediated negative feedback reinforces cAMP-induced neuronal differentiation in glioma stem cells

Accumulating evidence supports the existence of glioma stem cells (GSCs) and their critical role in the resistance to conventional treatments for glioblastoma multiforme (GBM). Differentiation therapy represents a promising alternative strategy against GBM by forcing GSCs to exit the cell cycle and...

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Detalles Bibliográficos
Autores principales: Chen, Zhijie, Zhong, Yingqian, Chen, Jiehong, Sun, Shuxin, Liu, Wenfeng, Han, Yu, Liu, Xincheng, Guo, Cui, Li, Depei, Hu, Wanming, Zhang, Peiyu, Chen, Zhuopeng, Chen, Zhongping, Mou, Yonggao, Yan, Guangmei, Zhu, Wenbo, Yin, Wei, Sai, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9130142/
https://www.ncbi.nlm.nih.gov/pubmed/35610201
http://dx.doi.org/10.1038/s41419-022-04957-9