Alteration in DNA-binding affinity of Wilms tumor 1 protein due to WT1 genetic variants associated with steroid - resistant nephrotic syndrome in children

Approximately one third of children with steroid-resistant nephrotic syndrome (SRNS) carry pathogenic variants in one of the many associated genes. The WT1 gene coding for the WT1 transcription factor is among the most frequently affected genes. Cases from the Czech national SRNS database were seque...

Descripción completa

Detalles Bibliográficos
Autores principales: Bezdicka, Martin, Kaufman, Filip, Krizova, Ivana, Dostalkova, Alzbeta, Rumlova, Michaela, Seeman, Tomas, Vondrak, Karel, Fencl, Filip, Zieg, Jakub, Soucek, Ondrej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9130146/
https://www.ncbi.nlm.nih.gov/pubmed/35610319
http://dx.doi.org/10.1038/s41598-022-12760-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9130146/
https://www.ncbi.nlm.nih.gov/pubmed/35610319
http://dx.doi.org/10.1038/s41598-022-12760-x

Ejemplares similares