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Extracellular vesicles derived from lung cancer cells exposed to intermittent hypoxia upregulate programmed death ligand 1 expression in macrophages

PURPOSE: Intermittent hypoxia (IH), a hallmark of obstructive sleep apnea (OSA), compromises immune surveillance through the upregulation of programmed cell death-1 ligand (PD-L1). Tumor-released extracellular vesicles (EVs) have been reported to modulate immunosuppressive activities. We investigate...

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Detalles Bibliográficos
Autores principales: Liu, Yuanling, Lu, Minzhen, Chen, Jianan, Li, Siqi, Deng, Yiyu, Yang, Shifang, Ou, Qiong, Li, Jing, Gao, Ping, Luo, Zeru, Yuan, Ping, Tan, Jianlong, Gao, Xinglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9130183/
https://www.ncbi.nlm.nih.gov/pubmed/34254261
http://dx.doi.org/10.1007/s11325-021-02369-1