Nkx2.8 promotes chemosensitivity in bladder urothelial carcinoma via transcriptional repression of MDR1

Multidrug resistance gene 1 (MDR1), a key factor contributing to drug insensitivity, has been associated with treatment failure and poor prognoses in various cancers, including bladder urothelial carcinoma (UC). Here we show that positive Nkx2.8 expression was associated with better prognosis of UC...

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Detalles Bibliográficos
Autores principales: Zhou, Zhaohui, Xiong, Longbin, Wu, Zeshen, Jiang, Lijuan, Li, Yonghong, Li, Zhiyong, Peng, Yulu, Ning, Kang, Zou, Xiangpeng, Liu, Zefu, Wang, Jun, Li, Zhen, Zhou, Fangjian, Liu, Zhuowei, Zhang, Zhiling, Yu, Chunping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9130207/
https://www.ncbi.nlm.nih.gov/pubmed/35610207
http://dx.doi.org/10.1038/s41419-022-04947-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9130207/
https://www.ncbi.nlm.nih.gov/pubmed/35610207
http://dx.doi.org/10.1038/s41419-022-04947-x

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