Vanilloid-dependent TRPV1 opening trajectory from cryoEM ensemble analysis

Single particle cryo-EM often yields multiple protein conformations within a single dataset, but experimentally deducing the temporal relationship of these conformers within a conformational trajectory is not trivial. Here, we use thermal titration methods and cryo-EM in an attempt to obtain tempora...

Descripción completa

Detalles Bibliográficos
Autores principales: Kwon, Do Hoon, Zhang, Feng, Fedor, Justin G., Suo, Yang, Lee, Seok-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9130279/
https://www.ncbi.nlm.nih.gov/pubmed/35610228
http://dx.doi.org/10.1038/s41467-022-30602-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9130279/
https://www.ncbi.nlm.nih.gov/pubmed/35610228
http://dx.doi.org/10.1038/s41467-022-30602-2

Ejemplares similares