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Vanilloid-dependent TRPV1 opening trajectory from cryoEM ensemble analysis
Single particle cryo-EM often yields multiple protein conformations within a single dataset, but experimentally deducing the temporal relationship of these conformers within a conformational trajectory is not trivial. Here, we use thermal titration methods and cryo-EM in an attempt to obtain tempora...
Autores principales: | Kwon, Do Hoon, Zhang, Feng, Fedor, Justin G., Suo, Yang, Lee, Seok-Yong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9130279/ https://www.ncbi.nlm.nih.gov/pubmed/35610228 http://dx.doi.org/10.1038/s41467-022-30602-2 |
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