An in vivo gene amplification system for high level expression in Saccharomyces cerevisiae

Bottlenecks in metabolic pathways due to insufficient gene expression levels remain a significant problem for industrial bioproduction using microbial cell factories. Increasing gene dosage can overcome these bottlenecks, but current approaches suffer from numerous drawbacks. Here, we describe HapAm...

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Detalles Bibliográficos
Autores principales: Peng, Bingyin, Esquirol, Lygie, Lu, Zeyu, Shen, Qianyi, Cheah, Li Chen, Howard, Christopher B., Scott, Colin, Trau, Matt, Dumsday, Geoff, Vickers, Claudia E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9130285/
https://www.ncbi.nlm.nih.gov/pubmed/35610221
http://dx.doi.org/10.1038/s41467-022-30529-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9130285/
https://www.ncbi.nlm.nih.gov/pubmed/35610221
http://dx.doi.org/10.1038/s41467-022-30529-8

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