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An in vivo gene amplification system for high level expression in Saccharomyces cerevisiae

Bottlenecks in metabolic pathways due to insufficient gene expression levels remain a significant problem for industrial bioproduction using microbial cell factories. Increasing gene dosage can overcome these bottlenecks, but current approaches suffer from numerous drawbacks. Here, we describe HapAm...

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Detalles Bibliográficos
Autores principales:	Peng, Bingyin, Esquirol, Lygie, Lu, Zeyu, Shen, Qianyi, Cheah, Li Chen, Howard, Christopher B., Scott, Colin, Trau, Matt, Dumsday, Geoff, Vickers, Claudia E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9130285/ https://www.ncbi.nlm.nih.gov/pubmed/35610221 http://dx.doi.org/10.1038/s41467-022-30529-8

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