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Structural insights into the ligand binding and G(i) coupling of serotonin receptor 5-HT(5A)

5-hydroxytryptamine receptor 5A (5-HT(5A)) belongs to the 5-HT receptor family and signals through the G(i/o) protein. It is involved in nervous system regulation and an attractive target for the treatment of psychosis, depression, schizophrenia, and neuropathic pain. 5-HT(5A) is the only G(i/o)-cou...

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Detalles Bibliográficos
Autores principales: Tan, Yangxia, Xu, Peiyu, Huang, Sijie, Yang, Gong, Zhou, Fulai, He, Xinheng, Ma, Honglei, Xu, H. Eric, Jiang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9130316/
https://www.ncbi.nlm.nih.gov/pubmed/35610220
http://dx.doi.org/10.1038/s41421-022-00412-3