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Activation of Gαq sequesters specific transcripts into Ago2 particles

The Gαq/phospholipase Cβ1 (PLCβ1) signaling system mediates calcium responses from hormones and neurotransmitters. While PLCβ1 functions on the plasma membrane, there is an atypical cytosolic population that binds Argonaute 2 (Ago2) and other proteins associated with stress granules preventing their...

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Detalles Bibliográficos
Autores principales: Jackson, Lela, Rennie, Madison, Poussaint, Alison, Scarlata, Suzanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9130320/
https://www.ncbi.nlm.nih.gov/pubmed/35610292
http://dx.doi.org/10.1038/s41598-022-12737-w