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Integrated Single Cell and Bulk RNA-Seq Analysis Revealed Immunomodulatory Effects of Ulinastatin in Sepsis: A Multicenter Cohort Study

Sepsis is a leading cause of morbidity and mortality in the intensive care unit, which is caused by unregulated inflammatory response leading to organ injuries. Ulinastatin (UTI), an immunomodulatory agent, is widely used in clinical practice and is associated with improved outcomes in sepsis. But i...

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Detalles Bibliográficos
Autores principales: Chen, Lin, Jin, Senjun, Yang, Min, Gui, Chunmei, Yuan, Yingpu, Dong, Guangtao, Zeng, Weizhong, Zeng, Jing, Hu, Guoxin, Qiao, Lujun, Wang, Jinhua, Xi, Yonglin, Sun, Jian, Wang, Nan, Wang, Minmin, Xing, Lifeng, Yang, Yi, Teng, Yan, Hou, Junxia, Bi, Qiaojie, Cai, Huabo, Zhang, Gensheng, Hong, Yucai, Zhang, Zhongheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9130465/
https://www.ncbi.nlm.nih.gov/pubmed/35634310
http://dx.doi.org/10.3389/fimmu.2022.882774