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The Bradykinin System Contributes to the Regulation of Prostaglandin-Endoperoxide Synthase 2 Expression in Human Amnion Fibroblasts: Implications for Term and Preterm Birth

BACKGROUND: Bradykinin (BK) and its biologically active metabolite des-Arg9 bradykinin (DABK) play a pivotal role in inflammation. Since chorioamnionitis is the leading cause of preterm birth and prostaglandin E2 (PGE2) derived from the amnion is key to labor initiation, we investigated if bradykini...

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Detalles Bibliográficos
Autores principales: Ni, Xiao-tian, Wang, Wang-sheng, Liu, Yun, Lin, Yi-kai, Zhang, Fan, Lei, Wen-jia, Ling, Li-jun, Pan, Fan, Zhu, Ya-nan, Li, Meng-die, Duan, Tao, Liu, Ming, Sun, Kang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9130483/
https://www.ncbi.nlm.nih.gov/pubmed/35634493
http://dx.doi.org/10.3389/fendo.2022.873727