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Prognostic significance of crown-like structures to trastuzumab response in patients with primary invasive HER2 + breast carcinoma
Obesity can initiate, promote, and maintain systemic inflammation via metabolic reprogramming of macrophages that encircle adipocytes, termed crown-like structures (CLS). In breast cancer the presence of CLS has been correlated to high body mass index (BMI), larger mammary adipocyte size and postmen...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9130517/ https://www.ncbi.nlm.nih.gov/pubmed/35610242 http://dx.doi.org/10.1038/s41598-022-11696-6 |