Prognostic significance of crown-like structures to trastuzumab response in patients with primary invasive HER2 + breast carcinoma

Obesity can initiate, promote, and maintain systemic inflammation via metabolic reprogramming of macrophages that encircle adipocytes, termed crown-like structures (CLS). In breast cancer the presence of CLS has been correlated to high body mass index (BMI), larger mammary adipocyte size and postmen...

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Detalles Bibliográficos
Autores principales: Birts, Charles N., Savva, Constantinos, Laversin, Stéphanie A., Lefas, Alicia, Krishnan, Jamie, Schapira, Aron, Ashton-Key, Margaret, Crispin, Max, Johnson, Peter W. M., Blaydes, Jeremy P., Copson, Ellen, Cutress, Ramsey I., Beers, Stephen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9130517/
https://www.ncbi.nlm.nih.gov/pubmed/35610242
http://dx.doi.org/10.1038/s41598-022-11696-6

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