In Vitro Effect of Mitochondria-Targeted Triphenylphosphonium-Based Compounds (Honokiol, Lonidamine, and Atovaquone) on the Platelet Function and Cytotoxic Activity

Introduction: Obtaining triphenylphosphonium salts derived from anticancer compounds to inhibit mitochondrial metabolism is of major interest due to their pivotal role in reactive oxygen species (ROS) production, calcium homeostasis, apoptosis, and cell proliferation. However, the use of this type o...

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Detalles Bibliográficos
Autores principales: Montecino-Garrido, Héctor, Méndez, Diego, Araya-Maturana, Ramiro, Millas-Vargas, Juan Pablo, Wehinger, Sergio, Fuentes, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9130573/
https://www.ncbi.nlm.nih.gov/pubmed/35645840
http://dx.doi.org/10.3389/fphar.2022.893873

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9130573/
https://www.ncbi.nlm.nih.gov/pubmed/35645840
http://dx.doi.org/10.3389/fphar.2022.893873

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