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In Vitro Effect of Mitochondria-Targeted Triphenylphosphonium-Based Compounds (Honokiol, Lonidamine, and Atovaquone) on the Platelet Function and Cytotoxic Activity
Introduction: Obtaining triphenylphosphonium salts derived from anticancer compounds to inhibit mitochondrial metabolism is of major interest due to their pivotal role in reactive oxygen species (ROS) production, calcium homeostasis, apoptosis, and cell proliferation. However, the use of this type o...
Autores principales: | Montecino-Garrido, Héctor, Méndez, Diego, Araya-Maturana, Ramiro, Millas-Vargas, Juan Pablo, Wehinger, Sergio, Fuentes, Eduardo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9130573/ https://www.ncbi.nlm.nih.gov/pubmed/35645840 http://dx.doi.org/10.3389/fphar.2022.893873 |
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