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Targeting the Type 5 Metabotropic Glutamate Receptor: A Potential Therapeutic Strategy for Neurodegenerative Diseases?

The type 5 metabotropic glutamate receptor, mGlu(5), has been proposed as a potential therapeutic target for the treatment of several neurodegenerative diseases. In preclinical neurodegenerative disease models, novel allosteric modulators have been shown to improve cognitive performance and reduce d...

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Detalles Bibliográficos
Autores principales: Budgett, Rebecca F., Bakker, Geor, Sergeev, Eugenia, Bennett, Kirstie A., Bradley, Sophie J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9130574/
https://www.ncbi.nlm.nih.gov/pubmed/35645791
http://dx.doi.org/10.3389/fphar.2022.893422