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Exploring the Causal Effect of Constipation on Parkinson’s Disease Through Mediation Analysis of Microbial Data

BACKGROUND AND AIMS: Parkinson’s disease (PD) is a worldwide neurodegenerative disease with an increasing global burden, while constipation is an important risk factor for PD. The gastrointestinal tract had been proposed as the origin of PD in Braak’s gut–brain axis hypothesis, and there is increasi...

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Detalles Bibliográficos
Autores principales: Fu, Shih-Chen, Shih, Ling-Chieh, Wu, Pei-Hua, Hsieh, Yi-Chen, Lee, Chung-Han, Lin, Sheng-Hsuan, Wang, Hsiuying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9130588/
https://www.ncbi.nlm.nih.gov/pubmed/35646722
http://dx.doi.org/10.3389/fcimb.2022.871710