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Auraptene ameliorates osteoporosis by inhibiting RANKL/NFATc1 pathway-mediated bone resorption based on network pharmacology and experimental evaluation

AIMS: The association of auraptene (AUR), a 7-geranyloxycoumarin, on osteoporosis and its potential pathway was predicted by network pharmacology and confirmed in experimental osteoporotic mice. METHODS: The network of AUR was constructed and a potential pathway predicted by Kyoto Encyclopedia of Ge...

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Detalles Bibliográficos
Autores principales: Kim, Mi H., Choi, La Y., Chung, Jae Y., Kim, Eun-Jung, Yang, Woong M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Editorial Society of Bone & Joint Surgery 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9130672/
https://www.ncbi.nlm.nih.gov/pubmed/35579298
http://dx.doi.org/10.1302/2046-3758.115.BJR-2021-0380.R1