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Auraptene ameliorates osteoporosis by inhibiting RANKL/NFATc1 pathway-mediated bone resorption based on network pharmacology and experimental evaluation
AIMS: The association of auraptene (AUR), a 7-geranyloxycoumarin, on osteoporosis and its potential pathway was predicted by network pharmacology and confirmed in experimental osteoporotic mice. METHODS: The network of AUR was constructed and a potential pathway predicted by Kyoto Encyclopedia of Ge...
Autores principales: | Kim, Mi H., Choi, La Y., Chung, Jae Y., Kim, Eun-Jung, Yang, Woong M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The British Editorial Society of Bone & Joint Surgery
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9130672/ https://www.ncbi.nlm.nih.gov/pubmed/35579298 http://dx.doi.org/10.1302/2046-3758.115.BJR-2021-0380.R1 |
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