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The Expression Modulation of the Key Enzyme Acc for Highly Efficient 3-Hydroxypropionic Acid Production

3-Hydroxypropionic acid (3-HP) is a promising high value-added chemical. Acetyl-CoA carboxylase (Acc) is a vital rate-limiting step in 3-HP biosynthesis through the malonyl-CoA pathway. However, Acc toxicity in cells during growth blocks its ability to catalyze acetyl-CoA to malonyl-CoA. The balanci...

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Detalles Bibliográficos
Autores principales: Wang, Sumeng, Jin, Xin, Jiang, Wei, Wang, Qian, Qi, Qingsheng, Liang, Quanfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9130761/
https://www.ncbi.nlm.nih.gov/pubmed/35633674
http://dx.doi.org/10.3389/fmicb.2022.902848