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Increase in Ca(2+)-Activated cAMP/PKA Signaling Prevents Hydroxychloroquine-Induced Bradycardia of the Cardiac Pacemaker

Bradycardia or tachycardia are known side effects of drugs that limit their clinical use. The heart pacemaker function which control the heart rate under normal conditions is determined by coupled clock system. Thus, interfering with specific clock mechanism will affect other clock mechanisms throug...

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Detalles Bibliográficos
Autores principales: Segal, Sofia, Arbel-Ganon, Limor, Mazgaoker, Savyon, Davoodi, Moran, Yaniv, Yael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9130770/
https://www.ncbi.nlm.nih.gov/pubmed/35634151
http://dx.doi.org/10.3389/fphys.2022.839140