Single-Cell Proteomics and Tumor RNAseq Identify Novel Pathways Associated With Clofazimine Sensitivity in PI- and IMiD- Resistant Myeloma, and Putative Stem-Like Cells

Multiple myeloma (MM) is an incurable plasma cell malignancy with dose-limiting toxicities and inter-individual variation in response/resistance to the standard-of-care/primary drugs, proteasome inhibitors (PIs), and immunomodulatory derivatives (IMiDs). Although newer therapeutic options are potent...

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Detalles Bibliográficos
Autores principales: Kumar, Harish, Mazumder, Suman, Sharma, Neeraj, Chakravarti, Sayak, Long, Mark D., Meurice, Nathalie, Petit, Joachim, Liu, Song, Chesi, Marta, Sanyal, Sabyasachi, Stewart, A. Keith, Kumar, Shaji, Bergsagel, Leif, Rajkumar, S. Vincent, Baughn, Linda B., Van Ness, Brian G., Mitra, Amit Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9130773/
https://www.ncbi.nlm.nih.gov/pubmed/35646666
http://dx.doi.org/10.3389/fonc.2022.842200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9130773/
https://www.ncbi.nlm.nih.gov/pubmed/35646666
http://dx.doi.org/10.3389/fonc.2022.842200

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