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The Alternative Sigma Factor SigL Influences Clostridioides difficile Toxin Production, Sporulation, and Cell Surface Properties

The alternative sigma factor SigL (Sigma-54) facilitates bacterial adaptation to the extracellular environment by modulating the expression of defined gene subsets. A homolog of the gene encoding SigL is conserved in the diarrheagenic pathogen Clostridioides difficile. To explore the contribution of...

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Detalles Bibliográficos
Autores principales: Clark, Andrew E., Adamson, Chelsea C., Carothers, Katelyn E., Roxas, Bryan Angelo P., Viswanathan, V. K., Vedantam, Gayatri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9130780/
https://www.ncbi.nlm.nih.gov/pubmed/35633701
http://dx.doi.org/10.3389/fmicb.2022.871152