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RNA Sequencing Reveals Alterations and Similarities in Cell Metabolism, Hypoxia and Immune Evasion in Primary Cell Cultures of Clear Cell Renal Cell Carcinoma

The treatment of advanced renal cell carcinoma remains a challenge. To develop novel therapeutic approaches, primary cell cultures as an in vitro model are considered more representative than commercial cell lines. In this study, we analyzed the gene expression of previously established primary cell...

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Detalles Bibliográficos
Autores principales: Simon, Adrian Georg, Esser, Laura Kristin, Ellinger, Jörg, Ritter, Manuel, Kristiansen, Glen, Muders, Michael H., Mayr, Thomas, Toma, Marieta Ioana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9130782/
https://www.ncbi.nlm.nih.gov/pubmed/35646693
http://dx.doi.org/10.3389/fonc.2022.883195