Genome Replication Is Associated With Release of Immunogenic DNA Waste

Innate DNA sensors detect foreign and endogenous DNA to induce responses to infection and cellular stress or damage. Inappropriate activation by self-DNA triggers severe autoinflammatory conditions, including Aicardi-Goutières syndrome (AGS) that can be caused by defects of the cytosolic DNase 3’rep...

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Detalles Bibliográficos
Autores principales: Schubert, Nadja, Schumann, Tina, Daum, Elena, Flade, Karolin, Ge, Yan, Hagedorn, Lara, Edelmann, Winfried, Müller, Luise, Schmitz, Marc, Kuut, Gunnar, Hornung, Veit, Behrendt, Rayk, Roers, Axel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9130835/
https://www.ncbi.nlm.nih.gov/pubmed/35634291
http://dx.doi.org/10.3389/fimmu.2022.880413

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9130835/
https://www.ncbi.nlm.nih.gov/pubmed/35634291
http://dx.doi.org/10.3389/fimmu.2022.880413

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