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Gestational Leucylation Suppresses Embryonic T‐Box Transcription Factor 5 Signal and Causes Congenital Heart Disease

Dysregulated maternal nutrition, such as vitamin deficiencies and excessive levels of glucose and fatty acids, increases the risk for congenital heart disease (CHD) in the offspring. However, the association between maternal amino‐acid levels and CHD is unclear. Here, it is shown that increased leuc...

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Detalles Bibliográficos
Autores principales: Zhang, Xuan, Liu, Lian, Chen, Wei‐Cheng, Wang, Feng, Cheng, Yi‐Rong, Liu, Yi‐Meng, Lai, Yang‐Fan, Zhang, Rui‐Jia, Qiao, Ya‐Nan, Yuan, Yi‐Yuan, Lin, Yan, Xu, Wei, Cao, Jing, Gui, Yong‐Hao, Zhao, Jian‐Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9130917/
https://www.ncbi.nlm.nih.gov/pubmed/35320615
http://dx.doi.org/10.1002/advs.202201034