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Alcohol induced increases in sperm Histone H3 lysine 4 trimethylation correlate with increased placental CTCF occupancy and altered developmental programming

Using a mouse model, studies by our group reveal that paternal preconception alcohol intake affects offspring fetal-placental growth, with long-lasting consequences on adult metabolism. Here, we tested the hypothesis that chronic preconception male alcohol exposure impacts histone enrichment in sper...

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Detalles Bibliográficos
Autores principales: Bedi, Yudhishtar S., Wang, Haiqing, Thomas, Kara N., Basel, Alison, Prunier, Julien, Robert, Claude, Golding, Michael C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9130987/
https://www.ncbi.nlm.nih.gov/pubmed/35614060
http://dx.doi.org/10.1038/s41598-022-12188-3