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Phenol-Soluble Modulins From Staphylococcus aureus Biofilms Form Complexes With DNA to Drive Autoimmunity

The bacterial amyloid curli, produced by Enterobacteriales including Salmonella species and Escherichia coli, is implicated in the pathogenesis of several complex autoimmune diseases. Curli binds to extracellular DNA, and these complexes drive autoimmunity via production of anti-double-stranded DNA...

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Detalles Bibliográficos
Autores principales: Grando, Kaitlyn, Nicastro, Lauren K., Tursi, Sarah A., De Anda, Jaime, Lee, Ernest Y., Wong, Gerard C. L., Tükel, Çağla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9131096/
https://www.ncbi.nlm.nih.gov/pubmed/35646719
http://dx.doi.org/10.3389/fcimb.2022.884065