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IGF2BP1 Promotes Proliferation of Neuroendocrine Neoplasms by Post-Transcriptional Enhancement of EZH2

SIMPLE SUMMARY: Neuroendocrine neoplasms (NEN) are very heterogeneous malignancies arising at different sites of the body that show an increasing incidence in recent decades. Here, we show that IGF2 mRNA binding protein 1 (IGF2BP1) is highly expressed in NEN cell lines, leading to enhanced cell prol...

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Detalles Bibliográficos
Autores principales: Sperling, Florian, Misiak, Danny, Hüttelmaier, Stefan, Michl, Patrick, Griesmann, Heidi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9131133/
https://www.ncbi.nlm.nih.gov/pubmed/35565249
http://dx.doi.org/10.3390/cancers14092121