Cargando…
IGF2BP1 Promotes Proliferation of Neuroendocrine Neoplasms by Post-Transcriptional Enhancement of EZH2
SIMPLE SUMMARY: Neuroendocrine neoplasms (NEN) are very heterogeneous malignancies arising at different sites of the body that show an increasing incidence in recent decades. Here, we show that IGF2 mRNA binding protein 1 (IGF2BP1) is highly expressed in NEN cell lines, leading to enhanced cell prol...
Autores principales: | Sperling, Florian, Misiak, Danny, Hüttelmaier, Stefan, Michl, Patrick, Griesmann, Heidi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9131133/ https://www.ncbi.nlm.nih.gov/pubmed/35565249 http://dx.doi.org/10.3390/cancers14092121 |
Ejemplares similares
-
IGF2BP1, a Conserved Regulator of RNA Turnover in Cancer
por: Glaß, Markus, et al.
Publicado: (2021) -
The oncofetal RNA-binding protein IGF2BP1 is a druggable, post-transcriptional super-enhancer of E2F-driven gene expression in cancer
por: Müller, Simon, et al.
Publicado: (2020) -
IGF2BP1: A post-transcriptional “driver” of tumor cell migration
por: Stöhr, Nadine, et al.
Publicado: (2012) -
IGF2BP1 is the first positive marker for anaplastic thyroid carcinoma diagnosis
por: Haase, Jacob, et al.
Publicado: (2020) -
IGF2BP1 enhances an aggressive tumor cell phenotype by impairing miRNA-directed downregulation of oncogenic factors
por: Müller, Simon, et al.
Publicado: (2018)