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Dapagliflozin induces vasodilation in resistance-size mesenteric arteries by stimulating smooth muscle cell K(V)7 ion channels
Dapagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor that, in addition to glucose reduction, lowers systemic blood pressure. Here, we investigated if dapagliflozin could directly relax small mesenteric arteries that control peripheral vascular resistance and blood pressure, and the un...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9131249/ https://www.ncbi.nlm.nih.gov/pubmed/35647331 http://dx.doi.org/10.1016/j.heliyon.2022.e09503 |