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Dapagliflozin induces vasodilation in resistance-size mesenteric arteries by stimulating smooth muscle cell K(V)7 ion channels

Dapagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor that, in addition to glucose reduction, lowers systemic blood pressure. Here, we investigated if dapagliflozin could directly relax small mesenteric arteries that control peripheral vascular resistance and blood pressure, and the un...

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Detalles Bibliográficos
Autores principales: Hasan, Ahasanul, Menon, Sreelakshmi N., Zerin, Farzana, Hasan, Raquibul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9131249/
https://www.ncbi.nlm.nih.gov/pubmed/35647331
http://dx.doi.org/10.1016/j.heliyon.2022.e09503