CLAffinity: A Software Tool for Identification of Optimum Ligand Affinity for Competition-Based Primary Screens

[Image: see text] A simplistic assumption in setting up a competition assay is that a low affinity labeled ligand can be more easily displaced from a target protein than a high affinity ligand, which in turn produces a more sensitive assay. An often-cited paper correctly rallies against this assumpt...

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Detalles Bibliográficos
Autores principales: Shave, Steven, Pham, Nhan T., Auer, Manfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9131445/
https://www.ncbi.nlm.nih.gov/pubmed/35442032
http://dx.doi.org/10.1021/acs.jcim.2c00285

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9131445/
https://www.ncbi.nlm.nih.gov/pubmed/35442032
http://dx.doi.org/10.1021/acs.jcim.2c00285

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